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Gina Rodriguez
Carmen Sandiego (voice)

Finn Wolfhard
Player (voice)

Abby Trott
Ivy (voice)

Micheal Hawley
Zack / Guard 1 (voice)

Liam O'Brien
Professor Maelstrom / Diplomat / Guard 2 (voice)

Mary Elizabeth McGlynn
Coach Brunt (voice)

Toks Olagundoye
Countess Cleo (voice)

Sharon Muthu
Doctor Bellum / Agent Zari (voice)

Kari Wahlgren
Sheena (Tigress) / Caterer (voice)

Andrew Pifko
Antonio (El Topo) (voice)

Bernardo de Paula
Jean Paul (Le Chevre) (voice)

Kimiko Glenn
Paperstar (voice)

Charlet Chung
Julia Argent (voice)

Dawnn Lewis
Chief (voice)