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Jim Conroy
Quincy Magoo (voice)

Dylan Sprouse
Justin Magoo (voice)

Cole Sprouse
Brad Landry (voice)

Alyson Stoner
Lorelei Tan Gu (voice)

Chris Parnell
Cole Fusion / Ninja (voice)

Kenny Mayne
Kenny Mayne (voice)

Jeff Bennett
Sid / Guard / Evil Mustache Cabal (voice)

Rodger Bumpass
General Smith / Driver / Mastermind (voice)

Maile Flanagan
Aliga-Tory / Orangu-Tammy (voice)

Lloyd Floyd
Tan Gu (voice)

Jennifer Hale
Leslie Destructo / Agent L / Dutch Boy (voice)

Tom Kenny
Dr. Malicio / Soldier (voice)

Ryan Bollman
Corporal Hayes / Biker (voice)

Candi Milo
Gor-Illiana / McBarker / Sid's Mom (voice)

April Stewart
Weas-Elizabeth / Girl with Phone (voice)

Jim Ward
General Bonkopp / Movie Announcer / Voice on Radio (voice)